Het-PDB Navi2 (PDB: 1KEW)

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Ligands
Code	Name	Link
GOL	Glycerol	PoSSuM
NAD	Nicotinamide-adenine-dinucleotide	PoSSuM
TYD	Thymidine-5'-diphosphate	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1KEW

Code :

1KEW PDBj RCSB PDB PDBe

Header :

LYASE

Title :

The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium with thymidine diphosphate bound

Release Data :

2002-01-25

Compound :

mol_id	molecule	chains	synonym
1	dTDP-D-glucose 4,6-dehydratase	A,B	dTDP-glucose 4,6-dehydratase; RmlB
	ec: 4.2.1.46

Source :

mol_id	organism_scientific	expression_system
1	Salmonella enterica subsp. enterica serovar Typhimurium (taxid:90371)	Escherichia coli BL21(DE3) (taxid:469008)
	strain: subsp. enterica serovar Typhimurium gene: rmlB expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: pET28

Authors :

Allard, S.T.M., Beis, K., Giraud, M.-F., Hegeman, A.D., Gross, J.W., Whitfield, C., Graninger, M., Messner, P., Allen, A.G., Naismith, J.H.

Keywords :

Rossmann fold, LYASE

Exp. method :

X-RAY DIFFRACTION ( 1.80 Å )

Citation :

Toward a structural understanding of the dehydratase mechanism.

Allard, S.T.,Beis, K.,Giraud, M.F. et al.
(2002) Structure 10 : 81 - 92

Chain :

A, B

UniProt :

P26391 (RMLB_SALTY)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O	4.2.1.46	PubMed:11796113
	-	PubMed:11796113

PDB ID: 1KEW