Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CA Calcium ion
YB Ytterbium (III) ion
3AT 3'-deoxyadenosine-5'-triphosphate
Code : 1K90
Header : TOXIN,LYASE/METAL BINDING PROTEIN
Title : Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP
Release Data : 2002-01-23
Compound :
mol_id molecule chains
1 CALMODULIN-SENSITIVE ADENYLATE CYCLASE A,B,C
ec: 4.6.1.1
mol_id molecule chains
2 CALMODULIN D,E,F
Source :
mol_id organism_scientific expression_system
1 Bacillus anthracis  (taxid:1392) Escherichia coli BL21  (taxid:511693)
expression_system_strain: BL21
expression_system_vector_type: PLASMID
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Escherichia coli BL21  (taxid:511693)
expression_system_strain: BL21
expression_system_vector_type: PLASMID
Authors : Drum, C.L., Yan, S.-Z., Bard, J., Shen, Y.-Q., Lu, D., Soelaiman, S., Grabarek, Z., Bohm, A., Tang, W.-J.
Keywords : oedema factor adenylyl cyclase anthrax calmodulin, TOXIN, LYASE-METAL BINDING PROTEIN COMPLEX
Exp. method : X-RAY DIFFRACTION ( 2.75 Å )
Citation :

Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.

Drum, C.L.,Yan, S.-Z.,Bard, J.  et al.
(2002)  Nature  415 : 396 - 402

PubMed: 11807546
DOI: 10.1038/415396a

Chain : A, B, C
UniProt : P40136 (CYAA_BACAN)
Reaction : ATP = 3',5'-cyclic AMP + diphosphate.
Chain : D, E, F
UniProt : P02593 (multiple entry names are found)
Reaction : -