Het-PDB Navi2 (PDB: 1K8L)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
C2S	Cytidine-5'-dithiophosphorate
G2S	Guanosine-5'-dithiophosphorate
T2S	Thymidine-5'-dithiophosphorate

Glycosylation
Code	Name	Emphasize

Modification
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Download interaction data: 1K8L

Code :

1K8L PDBj RCSB PDB PDBe

Header :

DNA

Title :

XBY6: An analog of CK14 containing 6 dithiophosphate groups

Release Data :

2003-04-15

Compound :

mol_id	molecule	chains
1	FIRST STRAND OF CK14 DNA DUPLEX	A
	fragment: DITHIOATED AT T10, C11 mutation: DITHIOATED AT T10, C11 other_details: CK14 IS A SUBUNIT OF THE NF-KB BINDING SITE CK1

mol_id	molecule	chains
2	SECOND STRAND OF CK14 DNA DUPLEX	B
	fragment: DITHIOATED AT G17, C22, C24, G27 mutation: DITHIOATED AT G17, C22, C24, G27 other_details: CK14 IS A SUBUNIT OF THE NF-KB BINDING SITE CK1

Source :

mol_id	organism_scientific
1
	synthetic: yes other_details: SYNTHESIZED WITH BOTH NORMAL PHOSPHOROAMIDITE CHEMISTRY AND THIOPHOSPHORAMIDITE CHEMISTRY

mol_id	organism_scientific
2
	synthetic: yes other_details: SYNTHESIZED WITH BOTH NORMAL PHOSPHOROAMIDITE CHEMISTRY AND THIOPHOSPHORAMIDITE CHEMISTRY

Authors :

Volk, D.E., Yang, X., Fennewald, S.M., King, D.J., Bassett, S.E., Venkitachalam, S., Herzog, N., Luxon, B.A., Gorenstein, D.G.

Keywords :

XBY6, CK14, CK1, PHOSPHORODITHIOATE, NF-KB, DNA

Exp. method :

SOLUTION NMR

Citation :

Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-kappaB

Volk, D.E.,Yang, X.,Fennewald, S.M. et al.
(2002) Bioorg.Chem. 30 : 396 - 419

PDB ID: 1K8L