PDB ID: 1K74
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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544 | 2-(1-methyl-3-oxo-3-phenyl-propylamino)-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid | PoSSuM | |||
9CR | (9cis)-retinoic acid | PoSSuM |
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Download interaction data: 1K74
Structure summary
Code : | 1K74 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | TRANSCRIPTION | ||||||||||||||||||||||||||||||||||||
Title : | The 2.3 Angstrom resolution crystal structure of the heterodimer of the human PPARgamma and RXRalpha ligand binding domains respectively bound with GW409544 and 9-cis retinoic acid and co-activator peptides. | ||||||||||||||||||||||||||||||||||||
Release Data : | 2001-12-05 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Authors : | Xu, H.E., Lambert, M.H., Montana, V.G., Moore, L.B., Collins, J.L., Oplinger, J.A., Kliewer, S.A., Gampe Jr., R.T., McKee, D.D., Moore, J.T., Willson, T.M. | ||||||||||||||||||||||||||||||||||||
Keywords : | The heterodimer of the nuclear receptor ligand binding domains of RXRalpha and PPARgamma bound respectively with 9-cis retinoic acid and GW409544 and coactivator peptides, TRANSCRIPTION | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.3 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors.
Xu, H.E.,Lambert, M.H.,Montana, V.G.
et al.
PubMed: 11698662 |
Reaction
Chain : | A |
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UniProt : | P19793 (RXRA_HUMAN) |
Reaction : | - |
Chain : | D |
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UniProt : | P37231 (PPARG_HUMAN) |
Reaction : | - |
Chain : | B, E | ||||||||
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UniProt : | O43792 (NCOA1_HUMAN) | ||||||||
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