Brand  (β version)

PDB ID: 1JVU

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Ligands
Code Name Style Show Link
C2P Cytidine-2'-monophosphate PoSSuM
Non-standard Residues
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Glycosylation
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Modification
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Structure summary

Code : 1JVU   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : CRYSTAL STRUCTURE OF RIBONUCLEASE A (COMPLEXED FORM)
Release Data : 2002-06-05
Compound :
mol_id molecule chains synonym
1 RIBONUCLEASE A A,B RNASE 1; RNASE A
ec: 3.1.27.5
other_details: COMPLEXED WITH CYTIDINE-2'-MONOPHOSPHATE
Source :
mol_id organism_scientific organism_common
1 Bos taurus  (taxid:9913) Cattle
organ: PANCREAS
Authors : Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L.
Keywords : PROTEIN DYNAMICS, PROTEIN STRUCTURE-FUNCTION, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 1.78 Å )
Citation :

Reversible Substrate-Induced Domain Motions in Ribonuclease A

Vitagliano, L.,Merlino, A.,Zagari, A.  et al.
(2002)  Proteins  46 : 97 - 104

PubMed: 11746706
DOI: 10.1002/prot.10033

Productive and Non-Productive Binding to Ribonuclease A: X-Ray Structure of Two Complexes with Uridylyl(2',5')Guanosine

Vitagliano, L.,Merlino, A.,Zagari, A.  et al.
(2000)  Protein Sci.  6 : 1217 - 1225

Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2',5')adenosine

Vitagliano, L.,Adinolfi, S.,Riccio, A.  et al.
(1998)  Protein Sci.  7 : 1691 - 1699

Reaction

Chain : A, B
UniProt : P61823 (RNAS1_BOVIN)
Reaction: EC: Evidence:
Physiological Direction:
an [RNA] containing cytidine + H2O = an [RNA]-3'-cytidine-3'- phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA]. 4.6.1.18 -
-
an [RNA] containing uridine + H2O = an [RNA]-3'-uridine-3'- phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA]. 4.6.1.18 -
-