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Ligands
Code Name Style Show Link
SO4 Sulfate ion
ET Ethidium
Non-standard Residues
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Glycosylation
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Code : 1JTY   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION
Title : Crystal structure of the multidrug binding transcriptional regulator QacR bound to ethidium
Release Data : 2001-12-12
Compound :
mol_id molecule chains synonym
1 HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION B,D,A,E QACR REPRESSOR, ORF 188
mutation: C72A, C141S
Source :
mol_id organism_scientific expression_system
1 Staphylococcus aureus  (taxid:1280) Escherichia coli  (taxid:562)
expression_system_strain: DH5a
expression_system_vector_type: plasmid
expression_system_plasmid: pSK5210
Authors : Schumacher, M.A., Miller, M.C., Grkovic, S., Brown, M.H., Skurray, R.A., Brennan, R.G.
Keywords : multidrug binding, multidrug recognition mechanism, cationic lipophilic drugs, QacR, QacA, repressor, transcription
Exp. method : X-RAY DIFFRACTION ( 2.97 Å )
Citation :

Structural mechanisms of QacR induction and multidrug recognition.

Schumacher, M.A.,Miller, M.C.,Grkovic, S.  et al.
(2001)  Science  294 : 2158 - 2163

PubMed: 11739955
DOI: 10.1126/science.1066020

Chain : B, D, A, E
UniProt : P0A0N4 (QACR_STAAU)
Reaction : -