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Ligands
Code Name Style Show Link
CFP 6-chloro-2-fluoropurine
MYS Pentadecane
Non-standard Residues
Code Name Show
Glycosylation
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Modification
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Code : 1JDJ   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH 2-FLUORO-6-CHLOROPURINE
Release Data : 2002-06-14
Compound :
mol_id molecule chains
1 GLYCEROL-3-PHOSPHATE DEHYDROGENASE A
ec: 1.1.1.8
Source :
mol_id organism_scientific expression_system
1 Leishmania mexicana  (taxid:5665) Escherichia coli BL21(DE3)  (taxid:469008)
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET3a
Authors : Suresh, S., Wisedchaisri, G., Kennedy, K.J., Verlinde, C.L.M.J., Gelb, M.H., Hol, W.G.J.
Keywords : dehydrogenase, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.2 Å )
Citation :

Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase.

Choe, J.,Suresh, S.,Wisedchaisri, G.  et al.
(2002)  Chem.Biol.  9 : 1189 - 1197

PubMed: 12445769
DOI: 10.1016/S1074-5521(02)00243-0

Chain : A
UniProt : P90551 (GPDA_LEIME)
Reaction: EC: Evidence:
Physiological Direction:
NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH 1.1.1.8 -
-