Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
GD Gadolinium atom
GLU Glutamic acid
Code : 1ISR
Header : SIGNALING PROTEIN
Title : Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion
Release Data : 2002-03-13
Compound :
mol_id molecule chains
1 Metabotropic Glutamate Receptor subtype 1 A
fragment: EXTRACELLULAR LIGAND BINDING REGION
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Norway rat Spodoptera frugiperda  (taxid:7108)
expression_system_common: Fall armyworm
expression_system_strain: SF9
expression_system_vector_type: BACULOVIRUS
Authors : Tsuchiya, D., Kunishima, N., Kamiya, N., Jingami, H., Morikawa, K.
Keywords : SIGNAL TRANSDUCTION, NEUROTRANSMITTER, G PROTEIN COUPLED RECEPTOR, AGONIST, GADOLINIUM ION, SIGNALING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 4.00 Å )
Citation :

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.

Tsuchiya, D.,Kunishima, N.,Kamiya, N.  et al.
(2002)  Proc.Natl.Acad.Sci.USA  99 : 2660 - 2665

PubMed: 11867751
DOI: 10.1073/pnas.052708599

Structural Basis of Glutamate Recognition by a Dimeric Metabotropic Glutamate Receptor

Kunishima, N.,Shimada, Y.,Tsuji, Y.  et al.
(2000)  Nature  407 : 971 - 977

DOI: 10.1038/35039564

Chain : A
UniProt : P23385 (GRM1_RAT)
Reaction : -