Het-PDB Navi2 (PDB: 1IGZ)

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Ligands
Code	Name	Link
COH	Protoporphyrin ix containing co	PoSSuM
EIC	Linoleic acid	PoSSuM
BGC	Beta-D-glucopyranose	PoSSuM
BOG	Octyl beta-D-glucopyranoside	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize
BMA	Beta-D-mannopyranose
MAN	Alpha-D-mannopyranose
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose
NDG	2-acetamido-2-deoxy-alpha-D-glucopyranose

Modification
Code	Name	Show

Download interaction data: 1IGZ

Code :

1IGZ PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

Crystal Structure of Linoleic acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.

Release Data :

2001-12-12

Compound :

mol_id	molecule	chains	synonym
1	Prostaglandin Endoperoxide H Synthase-1	A	cyclooxygenase
	ec: 1.14.99.1

Source :

mol_id	organism_scientific	organism_common
1	Ovis aries (taxid:9940)	Sheep
	organ: seminal vessicle

Authors :

Malkowski, M.G., Thuresson, E.D., Smith, W.L., Garavito, R.M.

Keywords :

membrane protein, fatty acid, linoleic acid, oxidoreductase, peroxidase, dioxygenase

Exp. method :

X-RAY DIFFRACTION ( 2.9 Å )

Citation :

Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1.

Malkowski, M.G.,Thuresson, E.D.,Lakkides, K.M. et al.
(2001) J.Biol.Chem. 276 : 37547 - 37555

Mutational and X-ray Crystallographic analysis of the Interaction of Dihomo-Gamma-Linolenic Acid with Prostaglandin Endoperoxide H Synthases.

Thuresson, E.D.,Malkowski, M.G.,Lakkides, K.M. et al.
(2001) J.Biol.Chem. 276 : 10358 - 10365

The Productive Conformation of Arachidonic Acid Bound to Prostaglandin Synthase.

Malkowski, M.G.,Ginell, S.L.,Smith, W.L. et al.
(2000) Science 289 : 1933 - 1937

PDB ID: 1IGZ