Het-PDB Navi2 (PDB: 1I7Z)

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Ligands
Code	Name		Style	Show	Link
COC	Cocaine				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1I7Z

Code :

1I7Z PDBj RCSB PDB PDBe

Header :

IMMUNE SYSTEM

Title :

ANTIBODY GNC92H2 BOUND TO LIGAND

Release Data :

2001-08-08

Compound :

mol_id	molecule	chains
1	CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	A,C
	other_details: THE CHIMERA CONSISTS OF RESIDUES 1-108 OF MOUSE PORTION AND 109-214 OF HUMAN PORTION OF IG KAPPA CHAIN.

mol_id	molecule	chains
2	CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	B,D
	other_details: THE CHIMERA CONSISTS OF RESIDUES 1-113 OF MOUSE PORTION AND 114-228 OF HUMAN PORTION OF IG GAMMA-1 CHAIN.

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Mus musculus, Homo sapiens (taxid:10090,9606)	House mouse, human	Escherichia coli BL21 (taxid:511693)
	strain: , expression_system_strain: BL21 expression_system_vector_type: PLASMID expression_system_plasmid: PET

mol_id	organism_scientific	organism_common	expression_system
2	Mus musculus, Homo sapiens (taxid:10090,9606)	House mouse, human	Escherichia coli BL21 (taxid:511693)
	strain: , expression_system_strain: BL21 expression_system_vector_type: PLASMID expression_system_plasmid: PET

Authors :

Larsen, N.A., Wilson, I.A.

Keywords :

IgG fold, antibody, chimera, IMMUNE SYSTEM

Exp. method :

X-RAY DIFFRACTION ( 2.3 Å )

Citation :

Crystal structure of a cocaine-binding antibody.

Larsen, N.A.,Zhou, B.,Heine, A. et al.
(2001) J.Mol.Biol. 311 : 9 - 15

PDB ID: 1I7Z