Het-PDB Navi2 (PDB: 1I7G)

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Ligands
Code	Name	Link
AZ2	(2s)-2-ethoxy-3-[4-(2-{4-[(methylsulfonyl)oxy]phenyl}ethoxy)phenyl]propanoic acid	PoSSuM
CPQ	N,N-bis(3-D-gluconamidopropyl)deoxycholamide	PoSSuM
NA	Sodium ion	PoSSuM

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Download interaction data: 1I7G

Code :

1I7G PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN FROM HUMAN PPAR-ALPHA IN COMPLEX WITH THE AGONIST AZ 242

Release Data :

2002-03-09

Compound :

mol_id	molecule	chains	synonym
1	PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA	A	PPAR-ALPHA
	fragment: LIGAND BINDING DOMAIN

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)

Authors :

Petersen, J.F.W., Cronet, P., Folmer, R., Blomberg, N., Sjoblom, K., Karlsson, U., Lindstedt, E.-L., Bamberg, K.

Keywords :

Anti parallel Helix Sandwich, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 2.20 Å )

Citation :

Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family.

Cronet, P.,Petersen, J.F.,Folmer, R. et al.
(2001) Structure 9 : 699 - 706

PDB ID: 1I7G