Brand  (β version)

PDB ID: 1I1A

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Ligands
Code Name Style Show Link
CYS Cysteine PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
BMA Beta-D-mannopyranose
FUC Alpha-L-fucopyranose
FUL Beta-L-fucopyranose
MAN Alpha-D-mannopyranose
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
NDG 2-acetamido-2-deoxy-alpha-D-glucopyranose
Modification
Code Name Show

Structure summary

Code : 1I1A   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : CRYSTAL STRUCTURE OF THE NEONATAL FC RECEPTOR COMPLEXED WITH A HETERODIMERIC FC
Release Data : 2001-02-14
Compound :
mol_id molecule chains synonym
1 NEONATAL FC RECEPTOR A A IGG RECEPTOR FCRN LARGE SUBUNIT P51, FCRN
fragment: EXTRACELLULAR DOMAIN
mol_id molecule chains synonym
2 BETA-2-MICROGLOBULIN B HDFC
fragment: FC FRAGMENT
mol_id molecule chains synonym
3 IG GAMMA-2A CHAIN C REGION C WTFC
fragment: WILD-TYPE FC FRAGMENT
mol_id molecule chains synonym
4 IG GAMMA-2A CHAIN C REGION D NBFC
fragment: NON-FCRN-BINDING FC FRAGMENT
mutation: T252G, I253G, T254G, H310E, H433E, H435E
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Norway rat Cricetulus griseus  (taxid:10029)
expression_system_common: Chinese hamster
expression_system_strain: CHO-K1
expression_system_vector_type: PLASMID
expression_system_plasmid: PBJ-5GS
mol_id organism_scientific organism_common expression_system
2 Rattus norvegicus  (taxid:10116) Norway rat Cricetulus griseus  (taxid:10029)
expression_system_common: Chinese hamster
expression_system_strain: CHO-K1
expression_system_vector_type: PLASMID
expression_system_plasmid: PBJ-5GS
mol_id organism_scientific organism_common expression_system
3 Rattus norvegicus  (taxid:10116) Norway rat Cricetulus griseus  (taxid:10029)
expression_system_common: Chinese hamster
expression_system_strain: CHO-K1
expression_system_vector_type: PLASMID
expression_system_plasmid: PBJ-5GS
mol_id organism_scientific organism_common expression_system
4 Rattus norvegicus  (taxid:10116) Norway rat Cricetulus griseus  (taxid:10029)
expression_system_common: Chinese hamster
expression_system_strain: CHO-K1
expression_system_vector_type: PLASMID
expression_system_plasmid: PBJ-5GS
Authors : Martin, W.L., West Jr., A.P., Gan, L., Bjorkman, P.J.
Keywords : MHC class I fold, Ig constant domains, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 2.80 Å )
Citation :

Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding.

Martin, W.L.,West Jr., A.P.,Gan, L.  et al.
(2001)  Mol.Cell  7 : 867 - 877

PubMed: 11336709
DOI: 10.1016/S1097-2765(01)00230-1

Reaction

Chain : A
UniProt : P13599 (FCGRN_RAT)
Reaction : -
Chain : B
UniProt : P07151 (B2MG_RAT)
Reaction : -
Chain : D
UniProt : P20760 (IGG2A_RAT)
Reaction : -