Brand  (β version)

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Ligands
Code Name Style Show Link
Non-standard Residues
Code Name Show
GPN 2-aminoethylglycine-carbonylmethylene-guanine
APN 2-aminoethylglycine-carbonylmethylene-adenine
TPN 2-aminoethylglycine-carbonylmethylene-thymine
CPN 2-aminoethylglycine-carbonylmethylene-cytosine
Glycosylation
Code Name Emphasize
Modification
Code Name Show
OPN {(2-amino-ethyl)-[2-(2-oxo-1,2-dihydro-[1,8]naphthyridin-3-yl)-acetyl]-amino}-acetic acid
NH2 Amino group
Code : 1HZS   PDBj   RCSB PDB   PDBe
Header : PEPTIDE NUCLEIC ACID
Title : Crystal structure of a peptide nucleic acid duplex (BT-PNA) containing a bicyclic analogue of thymine
Release Data : 2001-07-26
Compound :
mol_id molecule chains
1 PEPTIDE NUCLEIC ACID A,B,C,D
Source :
mol_id organism_scientific
1
synthetic: yes
other_details: Synthesized as described in the primary reference
Authors : Eldrup, A.B., Nielsen, B.B., Haaima, G., Rasmussen, H., Kastrup, J.S., Christensen, C., Nielsen, P.E.
Keywords : peptide nucleic acid, double helix, nucleobase analogue, P-form helix, left-handed, right-handed
Exp. method : X-RAY DIFFRACTION ( 1.82 Å )
Citation :

1,8-Naphthyridin-2(1H)-ones. Novel Bicyclic and Tricyclic Analogues of Thymine in Peptide Nucleic Acids (PNAs)

Eldrup, A.B.,Nielsen, B.B.,Haaima, G.  et al.
(2001)  Eur.J.Org.Chem.  9 : 1781 - 1790

PubMed: -1

Crystal Structure of a Peptide Nucleic Acid (PNA) Duplex at 1.7 A Resolution

Rasmussen, H.,Kastrup, J.S.,Nielsen, J.N.  et al.
(1997)  Nat.Struct.Biol.  4 : 98 - 101

Peptide Nucleic Acids (PNA) Derived from N-(N-methylaminoethyl)glycine. Synthesis, Hybridization and Structural Properties

Haima, G.,Rasmussen, H.,Schmidt, G.  et al.
(1999)  New J.Chem.  23 : 833 - 840

DOI: 10.1039/a902091h