Brand  (β version)

PDB ID: 1HXP

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Ligands
Code Name Style Show Link
BME Beta-mercaptoethanol PoSSuM
FE Fe (III) ion PoSSuM
U5P Uridine-5'-monophosphate PoSSuM
UDP Uridine-5'-diphosphate PoSSuM
ZN Zinc ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1HXP   PDBj   RCSB PDB   PDBe
Header : NUCLEOTIDYL TRANSFERASE
Title : NUCLEOTIDE TRANSFERASE
Release Data : 1996-11-08
Compound :
mol_id molecule chains synonym
1 HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE A,B ALPHA-D-GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE
ec: 2.7.7.10
other_details: GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE-UMP/UDP COMPLEX
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
cell_line: BL21
gene: GALT
expression_system_strain: BL21 (DE3) (PLYSS)
expression_system_vector_type: PET
expression_system_plasmid: PTZ18ROT
expression_system_gene: GALT
other_details: PET VECTOR SYSTEM
Authors : Wedekind, J.E., Frey, P.A., Rayment, I.
Keywords : METALLOENZYME, GALACTOSEMIA, NUCLEOTIDYL TRANSFERASE, COMPLEX (SERINE PROTEASE-INHIBITOR)
Exp. method : X-RAY DIFFRACTION ( 1.8 Å )
Citation :

Three-dimensional structure of galactose-1-phosphate uridylyltransferase from Escherichia coli at 1.8 A resolution.

Wedekind, J.E.,Frey, P.A.,Rayment, I.
(1995)  Biochemistry  34 : 11049 - 11061

PubMed: 7669762
DOI: 10.1021/bi00035a010

Galactose-1-Phosphate Uridylyltransferase from Escherichia Coli, a Zinc and Iron Metalloenzyme

Ruzicka, F.J.,Wedekind, J.E.,Kim, J.  et al.
(1995)  Biochemistry  34 : 5610

Crystallization and Preliminary Crystallographic Analysis of Galactose-1-Phosphate Uridylyltransferase from Escherichia Coli

Wedekind, J.E.,Frey, P.A.,Rayment, I.
(1994)  Acta Crystallogr.,Sect.D  50 : 329

Reaction

Chain : A, B
UniProt : P09148 (GAL7_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D- glucose 1-phosphate + UDP-alpha-D-galactose 2.7.7.12 PubMed:10529216, PubMed:10820011, PubMed:321007
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