Brand  (β version)

PDB ID: 1HKQ

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Ligands
Code Name Style Show Link
BEZ Benzoic acid PoSSuM
HG Mercury (II) ion PoSSuM
PO4 Phosphate ion PoSSuM
Non-standard Residues
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Structure summary

Code : 1HKQ   PDBj   RCSB PDB   PDBe
Header : DNA BINDING PROTEIN
Title : PPS10 plasmid DNA replication initiator protein RepA. Replication inactive, dimeric N-terminal domain.
Release Data : 2003-05-29
Compound :
mol_id molecule chains synonym
1 REPLICATION PROTEIN A,B REPA
fragment: N-TERMINAL DOMAIN DIMER, RESIDUES 2-133
other_details: PPS10 PLASMID DNA REPLICATION INITIATOR, REPLICATION INACTIVE, DIMERIC SPECIES
Source :
mol_id organism_scientific organism_common expression_system
1 PSEUDOMONAS SAVASTANOI  (taxid:29438) PSEUDOMONAS SYRINGAE PV. SAVASTANOI ESCHERICHIA COLI  (taxid:562)
expression_system_variant: SG22097
expression_system_plasmid: PRG-RECA-NHIS
Authors : Giraldo, R., Fernandez-Tornero, C., Evans, P.R., Diaz-Orejas, R., Romero, A.
Keywords : DNA BINDING PROTEIN, WINGED-HELIX, PPS10 PLASMID, REPLICATION INITIATOR DIMER.
Exp. method : X-RAY DIFFRACTION ( 2.75 Å )
Citation :

A Conformational Switch between Transcriptional Repression and Replication Initiation in Repa Dimerization Domain

Giraldo, R.,Fernandez-Tornero, C.,Evans, P.R.  et al.
(2003)  Nat.Struct.Biol.  10 : 496

PubMed: 12825085
DOI: 10.1038/NSB0703-496

Structural Changes in Repa, a Plasmid Replication Initiator, Upon Binding to Origin DNA

Diaz-Lopez, T.,Lages-Gonzalo, M.,Serrano-Lopez, A.  et al.
(2003)  J.Biol.Chem.  278 : 18606

PubMed: 12637554
DOI: 10.1074/JBC.M212024200

Common Domains in the Initiators of DNA Replication in Bacteria, Archaea and Eukarya: Combined Structural, Functional and Phylogenetic Perspectives

Giraldo, R.
(2003)  Fems Microbiol.Rev.  26 : 533

PubMed: 12586394
DOI: 10.1016/S0168-6445(02)00145-6

Protein Domains and Conformational Changes in the Activation of Repa, a DNA Replication Initiator

Giraldo, R.,Andreu, J.M.,Diaz-Orejas, R.
(1998)  Embo J.  17 : 4511

PubMed: 9687517
DOI: 10.1093/EMBOJ/17.15.4511

Genetic and Functional Analysis of the Basic Replicon of Pps10, a Plasmid Specific for Pseudomonas Isolated from Pseudomonas Syringae, Patovar Savastanoi

Nieto, C.,Giraldo, R.,Fernandez-Tresguerres, M.E.  et al.
(1992)  J.Mol.Biol.  223 : 415

PubMed: 1738155
DOI: 10.1016/0022-2836(92)90661-3

Reaction

Chain : A, B
UniProt : Q52546 (Q52546_PSESX)
Reaction : -