Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
5GP Guanosine-5'-monophosphate
SO4 Sulfate ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 1HGX   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE (GLYCOSYLTRANSFERASE)
Title : HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE (HGXPRTASE)
Release Data : 1996-08-17
Compound :
mol_id molecule chains synonym
1 HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE A,B HGXPRTASE
ec: 2.4.2.8
Source :
mol_id organism_scientific expression_system
1 Tritrichomonas foetus  (taxid:5724) Escherichia coli  (taxid:562)
strain: KV1
atcc: 30924
expression_system_plasmid: PBACE
Authors : Somoza, J.R., Wang, C.C., Fletterick, R.J.
Keywords : TRANSFERASE, GLYCOSYLTRANSFERASE, PURINE SALVAGE, TRANSFERASE (GLYCOSYLTRANSFERASE)
Exp. method : X-RAY DIFFRACTION ( 1.9 Å )
Citation :

Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus.

Somoza, J.R.,Chin, M.S.,Focia, P.J.  et al.
(1996)  Biochemistry  35 : 7032 - 7040

PubMed: 8679528
DOI: 10.1021/bi953072p

Isolation, Sequencing and Expression of the Gene Encoding Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase of Tritrichomonas Foetus

Chin, M.S.,Wang, C.C.
(1994)  Mol.Biochem.Parasitol.  63 : 221

Chain : A, B
UniProt : P51900 (HGXR_TRIFO)
Reaction: EC: Evidence:
Physiological Direction:
diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine 2.4.2.8 UniProtKB:Q26997
right-to-left
diphosphate + GMP = 5-phospho-alpha-D-ribose 1-diphosphate + guanine 2.4.2.8 UniProtKB:Q26997
right-to-left
diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine 2.4.2.22 UniProtKB:Q26997
right-to-left