Het-PDB Navi2 (PDB: 1HDC)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CBO	Carbenoxolone				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1HDC

Code :

1HDC PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

MECHANISM OF INHIBITION OF 3ALPHA,20BETA-HYDROXYSTEROID DEHYDROGENASE BY A LICORICE-DERIVED STEROIDAL INHIBITOR

Release Data :

1995-02-07

Compound :

mol_id	molecule	chains
1	3-ALPHA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE	A,B,C,D
	ec: 1.1.1.53

Source :

mol_id	organism_scientific
1	Streptomyces exfoliatus (taxid:1905)

Authors :

Ghosh, D.

Keywords :

OXIDOREDUCTASE

Exp. method :

X-RAY DIFFRACTION ( 2.20 Å )

Citation :

Mechanism of inhibition of 3 alpha, 20 beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor.

Ghosh, D.,Erman, M.,Wawrzak, Z. et al.
(1994) Structure 2 : 973 - 980

PubMed: 7866748
DOI: 10.1016/S0969-2126(94)00099-9

Inhibition of Streptomyces Hydrogenans 3Alpha,20Beta-Hydroxysteroid Dehydrogenase by Licorice-Derived Compounds and Crystallization of an Enzyme-Cofactor-Inhibitor Complex

Ghosh, D.,Erman, M.,Pangborn, W. et al.
(1992) J.Steroid Biochem.Mol.Biol. 42 : 849

Chain :

A, B, C, D

UniProt :

P19992 (HSD_STREX)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
androstan-3alpha,17beta-diol + NAD(+) = 17beta- hydroxyandrostanone + NADH + H(+)	1.1.1.53	-
	-	-

PDB ID: 1HDC

Hetero Atom Contents

Structure summary

Reaction