Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
FAD Flavin-adenine dinucleotide
FCA Alpha-D-fucose
GZZ N-{8-[(8-{[(E)-amino(imino)methyl]amino}octyl)amino]octyl}guanidine
MAN Alpha-D-mannose
NAG N-acetyl-D-glucosamine
Code : 1H82
Header : OXIDOREDUCTASE
Title : STRUCTURE OF POLYAMINE OXIDASE IN COMPLEX WITH GUAZATINE
Release Data : 2001-01-31
Compound :
mol_id molecule chains
1 POLYAMINE OXIDASE A,B,C
ec: 1.5.3.11
fragment: FAD-BINDING DOMAIN RESIDUES 29-500
Source :
mol_id organism_scientific organism_common
1 ZEA MAYS  (taxid:4577) MAIZE
Authors : Binda, C., Coda, A., Angelini, R., Federico, R., Ascenzi, P., Mattevi, A.
Keywords : FLAVIN-DEPENDENT AMINE OXIDASE, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.9 Å )
Citation :

Structural Bases for Inhibitor Binding and Catalysis in Polyamine Oxidase

Binda, C.,Angelini, R.,Federico, R.  et al.
(2001)  Biochemistry  40 : 2766

PubMed: 11258887
DOI: 10.1021/BI002751J

Chain : A, B, C
UniProt : O64411 (PAO_MAIZE)
Reaction : Spermidine + O(2) + H(2)O = propane-1,3- diamine + 4-aminobutanal +H(2)O(2).
N(8)-acetylspermidine + O(2) + H(2)O = propane-1,3-diamine + 4-acetamidobutanal + H(2)O(2).
Spermine + O(2) + H(2)O = N-(3-aminopropyl)-4- aminobutanal + trimethylenediamine + H(2)O(2).
N(1)-acetylspermine + O(2) + H(2)O = N-(3- acetamidopropyl)-4-aminobutanal + trimethylenediamine + H(2)O(2).