Brand  (β version)

PDB ID: 1H7T

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
C5P Cytidine-5'-monophosphate PoSSuM
SIA N-acetyl-alpha-neuraminic acid PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 1H7T   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogues, here complex with CMP-NeuAc
Release Data : 2001-09-13
Compound :
mol_id molecule chains synonym
1 3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE A,B CMP-KDO SYNTHETASE, CKS, CMP-2-KETO-3-DEOXYOCTULOSONIC ACID SYNTHETASE, CMP-2-KETO-3-DEOXY-MANNO -OCTONIC ACID SYNTHETASE
ec: 2.7.7.38
Source :
mol_id organism_scientific expression_system
1 ESCHERICHIA COLI  (taxid:562) ESCHERICHIA COLI  (taxid:562)
strain: K5
gene: KPSU
Authors : Jelakovic, S., Schulz, G.E.
Keywords : NUCLEOTIDYLTRANSFERASE, CMP-KDO SYNTHETASE, NUCLEOSIDE MONOPHOSPHATE GLYCOSIDES, LIPOPOLYSACCHARIDE BIOSYNTHESIS, SUGAR-ACTIVATING ENZYMES, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.48 Å )
Citation :

The Structure of Cmp:2-Keto-3-Deoxy-Manno-Octonic Acid Synthetase and of its Complexes with Substrates and Substrate Analogs

Jelakovic, S.,Schulz, G.E.
(2001)  J.Mol.Biol.  312 : 143

PubMed: 11545592
DOI: 10.1006/JMBI.2001.4948

The Three-Dimensional Structure of Capsule-Specific Cmp:2-Keto-3-Deoxy-Manno-Octonic Acid Synthetase from Escherichia Coli

Jelakovic, S.,Jann, K.,Schulz, G.E.
(1996)  FEBS Lett.  391 : 157

PubMed: 8706906
DOI: 10.1016/0014-5793(96)00724-7

Reaction

Chain : A, B
UniProt : P42216 (KPSU5_ECOLX)
Reaction: EC: Evidence:
Physiological Direction:
3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy- beta-D-manno-octulosonate + diphosphate 2.7.7.38 HAMAP- Rule:MF_00057
-