Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
DTP 2'-deoxyadenosine 5'-triphosphate
FE2 Fe (II) ion
MG Magnesium ion
Code : 1H7A
Header : OXIDOREDUCTASE
Title : Structural basis for allosteric substrate specificity regulation in class III ribonucleotide reductases: NRDD in complex with dATP
Release Data : 2002-03-28
Compound :
mol_id molecule chains synonym
1 ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN A ANAEROBIC NTP REDUCTASE
ec: 1.17.4.2
fragment: ACTIVE SITE SUBUNIT RESIDUES 1-605
mutation: YES
other_details: SEQUENCE DETERMINATION\: YOUNG, P., OHMAN, M., XU, M.Q.
Source :
mol_id organism_scientific expression_system
1 BACTERIOPHAGE T4  (taxid:10665) ESCHERICHIA COLI  (taxid:562)
expression_system_strain: JM109(DE3)
expression_system_plasmid: PET29T4NRDD(G580A)
Authors : Larsson, K.-M., Andersson, J., Sjoeberg, B.-M., Nordlund, P., Logan, D.T.
Keywords : OXIDOREDUCTASE, REDUCTASE, ALLOSTERIC REGULATION, SUBSTRATE SPECIFICITY
Exp. method : X-RAY DIFFRACTION ( 2.75 Å )
Citation :

Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase

Larsson, K.-M.,Andersson, J.,Sjoeberg, B.-M.  et al.
(2001)  Structure  9 : 739

PubMed: 11587648
DOI: 10.1016/S0969-2126(01)00627-X

Chain : A
UniProt : Q9T0V5 (NRDD_BPT4)
Reaction : 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H(2)O = ribonucleoside triphosphate + thioredoxin.