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Ligands
Code Name Style Show Link
CS Cesium ion
ACP Phosphomethylphosphonic acid adenylate ester
RIB Alpha-D-ribofuranose
Non-standard Residues
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Code : 1GQT   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Activation of Ribokinase by Monovalent Cations
Release Data : 2002-01-28
Compound :
mol_id molecule chains
1 RIBOKINASE A,B,C,D
ec: 2.7.1.15
Source :
mol_id organism_scientific expression_system
1 ESCHERICHIA COLI  (taxid:83333) ESCHERICHIA COLI  (taxid:562)
strain: K12
expression_system_strain: MRI240
expression_system_plasmid: PJGK10
Authors : Andersson, C.E., Mowbray, S.L.
Keywords : CARBOHYDRATE KINASE, RIBOSE, TRANSFERASE, INDUCED FIT, BINDING OF MONOVALENT CATIONS, ACTIVATION BY MONOVALENT CATIONS
Exp. method : X-RAY DIFFRACTION ( 2.34 Å )
Citation :

Activation of Ribokinase by Monovalent Cations.

Andersson, C.E.,Mowbray, S.L.
(2002)  J.Mol.Biol.  315 : 409

PubMed: 11786021
DOI: 10.1006/JMBI.2001.5248

Structure of Escherichia Coli Ribokinase in Complex with Ribose and Dinucleotide Determined to 1.8 A Resolution: Insights Into a New Family of Kinase Structures.

Sigrell, J.A.,Cameron, A.D.,Jones, T.A.  et al.
(1998)  Structure  6 : 183

PubMed: 9519409
DOI: 10.1016/S0969-2126(98)00020-3

Ribokinase from Escherichia Coli K12. Nucleotide Sequence and Overexpression of the Rbsk Gene and Purification of Ribokinase

Hope, J.N.,Bell, A.W.,Hermodson, M.A.  et al.
(1986)  J.Biol.Chem.  261 : 7663

PubMed: 3011794

Induced fit on sugar binding activates ribokinase.

Sigrell, J.A.,Cameron, A.D.,Mowbray, S.L.
(1999)  J. Mol. Biol.  290 : 1009 - 1018

PubMed: 10438599
DOI: 10.1006/jmbi.1999.2938

Chain : A, B, C, D
UniProt : P05054 (RBSK_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+) 2.7.1.15 HAMAP-Rule:MF_01987, PubMed:11563694, PubMed:16784868, PubMed:3011794
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