PDB ID: 1GFZ
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Structure summary
Code : | 1GFZ PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE | ||||||||||||
Release Data : | 2000-07-26 | ||||||||||||
Compound : |
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Source : |
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Authors : | Oikonomakos, N.G., Zographos, S.E., Skamnaki, V.T., Tsitsanou, K.E., Johnson, L.N. | ||||||||||||
Keywords : | GLYCOGEN PHOSPHORYLASE, GLYCOGEN METABOLISM, DIABETES, FLAVOPIRIDOL, INHIBITOR SITE, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.30 Å ) | ||||||||||||
Citation : |
Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site.
Oikonomakos, N.G.,Schnier, J.B.,Zographos, S.E.
et al.
PubMed: 10924512 A New Allosteric Site in Glycogen Phosphorylase b as a Target for Drug Interactions
Oikonomakos, N.G.,Skamnaki, V.T.,Tsitsanou, K.E.
et al.
Allosteric Inhibition of Glycogen Phosphorylase a by the Potential Antidiabetic Drug 3-Isopropyl 4-(2-Chlorophenyl)-1,4-Dihydro-1-Ethyl-2-Methyl-Pyridine-3,5,6-Tricarboxylate
Oikonomakos, N.G.,Tsitsanou, K.E.,Zographos, S.E.
et al.
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Reaction
Chain : | A | ||||||||
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UniProt : | P00489 (PYGM_RABIT) | ||||||||
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