Brand  (β version)

PDB ID: 1G7A

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Ligands
Code Name Style Show Link
ZN Zinc ion PoSSuM
CL Chloride ion PoSSuM
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Structure summary

Code : 1G7A   PDBj   RCSB PDB   PDBe
Header : hormone/growth factor
Title : 1.2 A structure of T3R3 human insulin at 100 K
Release Data : 2001-08-03
Compound :
mol_id molecule chains
1 INSULIN A-CHAIN A,C,E,G
fragment: A-CHAIN
mol_id molecule chains
2 INSULIN B-CHAIN B,D,F,H
fragment: B-CHAIN
Source :
mol_id organism_scientific
1
synthetic: yes
other_details: This sequence occurs naturally in homo sapiens (Human)
mol_id organism_scientific
2
synthetic: yes
other_details: This sequence occurs naturally in homo sapiens (Human)
Authors : Smith, G.D., Pangborn, W.A., Blessing, R.H.
Keywords : T3R3 Insulin Hexamer, hormone-growth factor COMPLEX
Exp. method : X-RAY DIFFRACTION ( 1.2 Å )
Citation :

Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced?

Smith, G.D.,Pangborn, W.A.,Blessing, R.H.
(2001)  Acta Crystallogr.,Sect.D  57 : 1091 - 1100

PubMed: 11468392
DOI: 10.1107/S0907444901007685

X-ray Crystallographic Studies on Hexameric Insulins in the Presence of Helix-Stabilizing Agents, Thiocyanate, Methylparaben, and Phenol

Whittingham, J.L.,Chaudhuri, S.,Dodson, E.J.  et al.
(1995)  Biochemistry  34 : 15553 - 15563

Crystallographic Evidence for Dual Coordination around Zinc in the T3R3 Human Insulin Hexamer

Ciszak, E.,Smith, G.D.
(1994)  Biochemistry  33 : 1512 - 1517

Structural stability in the 4-zinc human insulin hexamer

Smith, G.D.,Swenson, D.C.,Dodson, E.J.  et al.
(1984)  Proc.Natl.Acad.Sci.USA  81 : 7093 - 7097

Structure of 4-zinc insulin

Bentley, G.,Dodson, E.,Dodson, G.G.  et al.
(1976)  Nature  261 : 166 - 168

The First Protein Crystal Structure Determined from High Resolution X-Ray Powder Diffraction Data: A Variant of T3R3 Human Insulin Zinc Complex Produced by Grinding

Von Dreele, R.B.,Stephens, P.W.,Smith, G.D.  et al.
(2000)  Acta Crystallogr.,Sect.D  56 : 1549

DOI: 10.1107/S0907444900013901

Reaction

Chain : B, D, F, H
UniProt : P01308 (INS_HUMAN)
Reaction : -