Het-PDB Navi2 (PDB: 1G5L)

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Ligands
Code	Name	Link
3CO	Cobalt (III) ion	PoSSuM
BLB	Bleomycin b2	PoSSuM
O	Oxygen atom	PoSSuM
PEO	Hydrogen peroxide	PoSSuM
PGA	2-phosphoglycolic acid	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1G5L

Code :

1G5L PDBj RCSB PDB PDBe

Header :

DNA

Title :

CO(III)-BLEOMYCIN-OOH BOUND TO AN OLIGONUCLEOTIDE CONTAINING A PHOSPHOGLYCOLATE LESION

Release Data :

2001-06-06

Compound :

mol_id	molecule	chains
1	5'-D(CPCPAPAPAPG)-3'	A

mol_id	molecule	chains
2	5'-D(PAPCPTPGPGPG)-3'	B

mol_id	molecule	chains
3	5'-D(CPCPCPAPGPTPAPCPTPTPTPGP*G)-3'	C

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

mol_id	organism_scientific
3
	synthetic: yes

Authors :

Hoehn, S.T., Junker, H.-D., Bunt, R.C., Turner, C.J., Stubbe, J.

Keywords :

damaged DNA, DNA-drug complex, intercalation, DNA

Exp. method :

SOLUTION NMR

Citation :

Solution structure of Co(III)-bleomycin-OOH bound to a phosphoglycolate lesion containing oligonucleotide: implications for bleomycin-induced double-strand DNA cleavage.

Hoehn, S.T.,Junker, H.D.,Bunt, R.C. et al.
(2001) Biochemistry 40 : 5894 - 5905

PubMed: 11352724
DOI: 10.1021/bi002635g

PDB ID: 1G5L

Hetero Atom Contents

Structure summary