Brand  (β version)

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Ligands
Code Name Link
CP Phosphoric acid mono(formamide)ester
Code : 1FVO
Header : TRANSFERASE
Title : CRYSTAL STRUCTURE OF HUMAN ORNITHINE TRANSCARBAMYLASE COMPLEXED WITH CARBAMOYL PHOSPHATE
Release Data : 2001-04-04
Compound :
mol_id molecule chains synonym
1 ORNITHINE TRANSCARBAMYLASE A,B OTCASE
ec: 2.1.3.3
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
expression_system_plasmid: PET 21A+
Authors : Shi, D., Morizono, H., Yu, X., Allewell, N.M., Tuchman, M.
Keywords : Two domains, alpha/beta topology, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.60 Å )
Citation :

Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes.

Shi, D.,Morizono, H.,Yu, X.  et al.
(2001)  Biochem.J.  354 : 501 - 509

PubMed: 11237854
DOI: 10.1042/0264-6021:3540501

Crystal Structure of Human Ornithine Transcarbamylase Complexed with Carbamoyl Phosphate and L-norvaline at 1.9 A Resolution

Shi, D.,Morizono, H.,Aoyagi, M.  et al.
(2000)  Proteins  39 : 271 - 277

DOI: 10.1002/(SICI)1097-0134(20000601)39:4<271::AID-PROT10>3.3.CO;2-5

Chain : A, B
UniProt : P00480 (OTC_HUMAN)
Reaction : Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.