Brand  (β version)

PDB ID: 1FS5

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
TLA L(+)-tartaric acid PoSSuM
16G 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 1FS5   PDBj   RCSB PDB   PDBe
Header : ISOMERASE
Title : A DISCOVERY OF THREE ALTERNATE CONFORMATIONS IN THE ACTIVE SITE OF GLUCOSAMINE-6-PHOSPHATE ISOMERASE
Release Data : 2002-01-04
Compound :
mol_id molecule chains synonym
1 GLUCOSAMINE-6-PHOSPHATE DEAMINASE A,B GLUCOSAMINE-6-PHOSPHATE DEAMINASE, GNPDA, GLCN6P DEAMINASE
ec: 5.3.1.10
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
expression_system_vector_type: PLASMID
expression_system_plasmid: PTZ18-R
Authors : Rudino-Pinera, E., Morales-Arrieta, S., Rojas-Trejo, S.P., Horjales, E.
Keywords : ALLOSTERIC ENZYME, ENTROPIC EFFECTS, ALDOSE-KETOSE ISOMERASE, MULTIPLE CONFORMERS, ISOMERASE
Exp. method : X-RAY DIFFRACTION ( 1.73 Å )
Citation :

Structural flexibility, an essential component of the allosteric activation in Escherichia coli glucosamine-6-phosphate deaminase.

Rudino-Pinera, E.,Morales-Arrieta, S.,Rojas-Trejo, S.P.  et al.
(2002)  Acta Crystallogr.,Sect.D  58 : 10 - 20

PubMed: 11752775
DOI: 10.1107/S0907444901016699

Structure and catalytic mechanism of glucosamine-6-phosphate deaminase from Escherichia coli at 2.1A resolution

Oliva, G.,Fontes, M.R.M.,Garratt, R.C.  et al.
(1995)  Structure  3 : 1323 - 1332

The allosteric transition of glucosamine-6-phosphate deaminase: the structure of the T state at 2.3A resolution

Horjales, E.,Altamirano, M.M.,Calcagno, M.L.  et al.
(1999)  Structure  7 : 527 - 537

DOI: 10.1016/S0969-2126(99)80069-0

Reaction

Chain : A, B
UniProt : P0A759 (NAGB_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6- phosphate + NH4(+) 3.5.99.6 PubMed:1734962, PubMed:2821923
-