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Ligands
Code Name Style Show Link
AMP Adenosine monophosphate
ZN Zinc ion
FDP 2,6-di-O-phosphono-beta-D-fructofuranose
Non-standard Residues
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Glycosylation
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Code : 1FRP   PDBj   RCSB PDB   PDBe
Header : HYDROLASE(PHOSPHORIC MONOESTER)
Title : CRYSTAL STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH FRUCTOSE-2,6-BISPHOSPHATE, AMP AND ZN2+ AT 2.0 ANGSTROMS RESOLUTION. ASPECTS OF SYNERGISM BETWEEN INHIBITORS
Release Data : 1994-11-30
Compound :
mol_id molecule chains
1 FRUCTOSE 1,6-BISPHOSPHATASE A,B
ec: 3.1.3.11
Source :
mol_id organism_scientific organism_common
1 Sus scrofa  (taxid:9823) Pig
Authors : Xue, Y., Huang, S., Liang, J.-Y., Zhang, Y., Lipscomb, W.N.
Keywords : HYDROLASE(PHOSPHORIC MONOESTER)
Exp. method : X-RAY DIFFRACTION ( 2.0 Å )
Citation :

Crystal structure of fructose-1,6-bisphosphatase complexed with fructose 2,6-bisphosphate, AMP, and Zn2+ at 2.0-A resolution: aspects of synergism between inhibitors.

Xue, Y.,Huang, S.,Liang, J.Y.  et al.
(1994)  Proc.Natl.Acad.Sci.USA  91 : 12482 - 12486

PubMed: 7809062
DOI: 10.1073/pnas.91.26.12482

Crystallographic Studies of the Catalytic Mechanism of the Neutral Form of Fructose-1,6-Bisphosphatase

Zhang, Y.,Liang, J.-Y.,Huang, S.  et al.
(1993)  Biochemistry  32 : 1844

Crystal Structure of the Neutral Form of Fructose 1,6-Bisphosphatase Complexed with Regulatory Inhibitor Fructose 2,6-Bisphosphate at 2.6 Angstroms Resolution

Liang, J.-Y.,Huang, S.,Zhang, Y.  et al.
(1992)  Proc.Natl.Acad.Sci.USA  89 : 2404

Conformational Transition of Fructose 1,6-Bisphosphatase: Structure Comparison between the AMP Complex (T Form) and the Fructose 6-Phosphate Complex (R Form)

Ke, H.,Liang, J.-Y.,Zhang, Y.  et al.
(1991)  Biochemistry  30 : 4412

Chain : A, B
UniProt : P00636 (F16P1_PIG)
Reaction: EC: Evidence:
Physiological Direction:
beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6- phosphate + phosphate 3.1.3.11 PubMed:15767255, PubMed:1313579
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