Brand  (β version)

PDB ID: 1FPM

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Ligands
Code Name Style Show Link
SO4 Sulfate ion PoSSuM
CS Cesium ion PoSSuM
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Structure summary

Code : 1FPM   PDBj   RCSB PDB   PDBe
Header : LIGASE
Title : MONOVALENT CATION BINDING SITES IN N10-FORMYLTETRAHYDROFOLATE SYNTHETASE FROM MOORELLA THERMOACETICA
Release Data : 2001-08-31
Compound :
mol_id molecule chains synonym
1 FORMATE--TETRAHYDROFOLATE LIGASE A,B FORMYLTETRAHYDROFOLATE SYNTHETASE
ec: 6.3.4.3
Source :
mol_id organism_scientific expression_system
1 Moorella thermoacetica  (taxid:1525) Escherichia coli  (taxid:562)
expression_system_vector_type: PLASMID
expression_system_plasmid: PCRL47 S2A
Authors : Radfar, R., Leaphart, A., Brewer, J.M., Minor, W., Odom, J.D.
Keywords : MONOVALENT CATION, THERMOSTABLE, TETRAMER, LIGASE
Exp. method : X-RAY DIFFRACTION ( 3.00 Å )
Citation :

Cation binding and thermostability of FTHFS monovalent cation binding sites and thermostability of N10-formyltetrahydrofolate synthetase from Moorella thermoacetica.

Radfar, R.,Leaphart, A.,Brewer, J.M.  et al.
(2000)  Biochemistry  39 : 14481 - 14486

PubMed: 11087401
DOI: 10.1021/bi001577w

Reaction

Chain : A, B
UniProt : P21164 (FTHS_MOOTH)
Reaction: EC: Evidence:
Physiological Direction:
(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate 6.3.4.3 HAMAP-Rule:MF_01543
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