Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
DDQ Decylamine-N,N-dimethyl-N-oxide
DPO Diphosphate
FTT 3-hydroxy-tetradecanoic acid
MG Magnesium ion
NA Sodium ion
NI Nickel (II) ion
PO4 Phosphate ion
RIF Rifamycin cgp 4832
Modified Residues
Code Name Link
GCN 2-amino-2,3-dideoxy-alpha-D-glucoyranose
GLA Alpha-D-galactopyranose
GLC Alpha-D-glucopyranose
GMH L-glycero-alpha-D-manno-heptopyranose
KDO 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid
PA1 2-amino-2-deoxy-alpha-D-glucopyranose
Code : 1FI1
Header : METAL TRANSPORT
Title : FhuA in complex with lipopolysaccharide and rifamycin CGP4832
Release Data : 2001-08-29
Compound :
mol_id molecule chains
1 FERRICHROME-IRON RECEPTOR A
mutation: HEXAHISTIDINE TAG PLUS FIVE LINKER RESIDUES HAVE BEEN GENETICALLY INSERTED AFTER RESIDUE 405 OF THE MATURE SEQUENCE
Source :
mol_id organism_scientific expression_system
1 Escherichia coli K12  (taxid:83333) Escherichia coli  (taxid:562)
strain: K-12
cellular_location: OUTER MEMBRANE
expression_system_vector: PLASMID-ENCODED HEXAHISTIDINE-TAGGED FHUA
Authors : Ferguson, A.D., Koedding, J., Boes, C., Walker, G., Coulton, J.W., Diederichs, K., Braun, V., Welte, W.
Keywords : Outer membrane protein; TonB-dependent receptor; FhuA; siderophore receptor; integral membrane protein; lipopolysaccharide; rifamycin CGP 4832; beta-barrel; antibiotic, METAL TRANSPORT
Exp. method : X-RAY DIFFRACTION ( 2.90 Å )
Citation :

Active transport of an antibiotic rifamycin derivative by the outer-membrane protein FhuA.

Ferguson, A.D.,Kodding, J.,Walker, G.  et al.
(2001)  Structure  9 : 707 - 716

PubMed: 11587645
DOI: 10.1016/S0969-2126(01)00631-1

A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins

Ferguson, A.D.,Welte, W.,Hofmann, E.  et al.
(2000)  Structure  8 : 585 - 592

DOI: 10.1016/S0969-2126(00)00143-X

Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA

Ferguson, A.D.,Braun, V.,Fiedler, H.-P.  et al.
(2000)  Protein Sci.  9 : 956 - 963

Siderophore-mediated iron transport: Crystal structure of FhuA with bound lipopolysaccharide

Ferguson, A.D.,Hofmann, E.,Coulton, J.W.  et al.
(1998)  Science  282 : 2215 - 2220

DOI: 10.1126/science.282.5397.2215

Chain : A
UniProt : P06971 (FHUA_ECOLI)
Reaction : -