Brand  (β version)

PDB ID: 1FDG

Hetero Atom Contents

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Code Name Style Show Link
9TA 1,4-bis-[2-(2-hydroxy-ethylamino)-ethylamino]-anthraquinone PoSSuM
CO Cobalt (II) ion PoSSuM
MG Magnesium ion PoSSuM

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Structure summary

Code : 1FDG   PDBj   RCSB PDB   PDBe
Header : DNA
Title : BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (AMETANTRONE COMPLEX)
Release Data : 2000-08-07
Compound :
mol_id molecule chains
1 DNA (5'-D(*CP*GP*TP*AP*CP*G)-3') A,B
Source :
mol_id organism_scientific
1 Synthetic construct  (taxid:32630)
synthetic: yes
other_details: synthetic DNA moleclue
Authors : Yang, X.-L., Robinson, H., Gao, Y.-G., Wang, A.H.-J.
Keywords : High resolution crystal structure, intercalation platform, MAD, anticancer drug, drug-DNA complex, metal ions, tertiary base pairs, DNA
Exp. method : X-RAY DIFFRACTION ( 1.6 Å )
Citation :

Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.

Yang, X.L.,Robinson, H.,Gao, Y.G.  et al.
(2000)  Biochemistry  39 : 10950 - 10957

PubMed: 10998231
DOI: 10.1021/bi001319z