Brand  (β version)

PDB ID: 1FC8

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Ligands
Code Name Style Show Link
Non-standard Residues
Code Name Show
CFL 4-amino-1-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)pyrimidin-2(1h)-one
GFL 2-amino-9-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)-1,9-dihydro-6h-purin-6-one
TAF 2'-deoxy-2'-fluoro-arabino-furanosyl thymine-5'-phosphate
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 1FC8   PDBj   RCSB PDB   PDBe
Header : RNA/DNA CHIMERA
Title : NMR SOLUTION STRUCTURE OF A CHIMERIC OLIGONUCLEOTIDE HAIRPIN R(GGAC)D(TTCG)2'F-A(GTCC)
Release Data : 2001-05-30
Compound :
mol_id molecule chains synonym
1 5'-R(*GP*GP*AP*CP)D(*TP*TP*CP*GP*(GFL)P*(TAF)P*(CFL)P*(CFL))-3' A RNA/2'F-ANA HAIRPIN
Source :
mol_id organism_scientific
1
synthetic: yes
other_details: SOLID PHASE SYNTHESIS; PHOSPHORAMIDITE CHEMISTRY
Authors : Trempe, J.-F., Gehring, K.
Keywords : 2'F-ARABINONUCLEIC ACID, RNA, DNA, HYBRID DUPLEX, HAIRPIN, RNA-DNA CHIMERA COMPLEX
Exp. method : SOLUTION NMR
Citation :

NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes.

Trempe, J.F.,Wilds, C.J.,Denisov, A.Y.  et al.
(2001)  J.Am.Chem.Soc.  123 : 4896 - 4903

PubMed: 11457316
DOI: 10.1021/ja003859p