Het-PDB Navi2 (PDB: 1FAV)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
GGL	Gamma-L-glutamic acid

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show
3PA	3-cyclopentyl-propionic acid
4BA	4-[(2-carboxy-ethylamino)-methyl]-benzoic acid

Download interaction data: 1FAV

Code :

1FAV PDBj RCSB PDB PDBe

Header :

VIRAL PROTEIN

Title :

THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE

Release Data :

2000-08-23

Compound :

mol_id	molecule	chains
1	HIV-1 ENVELOPE PROTEIN CHIMERA	A
	mutation: L2I, V6I, L9I, N13I, L16I, V20I, L23I, V27I other_details: CHIMERA CONSISTS OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO A FRAGMENT OF GP41

mol_id	molecule	chains
2	PROTEIN (TRANSMEMBRANE GLYCOPROTEIN)	C
	fragment: OUTER PEPTIDE OF GP41 OF HIV-1

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (taxid:559292)	Baker's yeast	Escherichia coli (taxid:562)
	gene: GCN4,AAS3,ARG9,YEL009C expression_system_plasmid: PRSET

mol_id	organism_scientific
2
	synthetic: yes other_details: The peptide was chemically synthesized. The sequence of the peptide is naturally found in HIV-1.

Authors :

Zhou, G., Ferrer, M., Chopra, R., Strassmaier, T., Weissenhorn, W., Skehel, J.J., Oprian, D., Schreiber, S.L., Harrison, S.C., Wiley, D.C.

Keywords :

HIV-1, gp41, inhibitor, Viral protein

Exp. method :

X-RAY DIFFRACTION ( 3.0 Å )

Citation :

The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core.

Zhou, G.,Ferrer, M.,Chopra, R. et al.
(2000) Bioorg.Med.Chem. 8 : 2219 - 2227

PDB ID: 1FAV