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Ligands
Code Name Style Show Link
CPS 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate
SO4 Sulfate ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
FUC Alpha-L-fucopyranose
MAN Alpha-D-mannopyranose
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
Code Name Show
Code : 1F6A   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)ri(alpha)
Release Data : 2000-07-20
Compound :
mol_id molecule chains synonym
1 HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT A HIGH AFFINITY IGE-FC RECEPTOR, FC(EPSILON)RI(ALPHA)
fragment: EXTRACELLULAR DOMAIN
mutation: N74A,N135A,T142A,V143A
mol_id molecule chains synonym
2 IG EPSILON CHAIN C REGION B,D IGE-FC
fragment: C(EPSILON)3-C(EPSILON)4 DOMAINS
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human HI-5 INSECT CELLS
expression_system_common: HI-5 INSECT CELLS
expression_system_vector_type: BACULOVIRUS
expression_system_plasmid: PVL1392
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human HI-5 INSECT CELLS
expression_system_common: HI-5 INSECT CELLS
expression_system_vector_type: BACULOVIRUS
expression_system_plasmid: PVL1392
Authors : Garman, S.C., Wurzburg, B.A., Tarchevskaya, S.S., Kinet, J.P., Jardetzky, T.S.
Keywords : IMMUNOGLOBULIN FOLD, GLYCOPROTEIN, RECEPTOR, IGE-BINDING PROTEIN, IGE ANTIBODY, IGE-FC, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 3.50 Å )
Citation :

Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc (epsilon) RI (alpha).

Garman, S.C.,Wurzburg, B.A.,Tarchevskaya, S.S.  et al.
(2000)  Nature  406 : 259 - 266

PubMed: 10917520
DOI: 10.1038/35018500

Chain : A
UniProt : P12319 (FCERA_HUMAN)
Reaction : -
Chain : B, D
UniProt : P01854 (IGHE_HUMAN)
Reaction : -