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Ligands
Code Name Style Show Link
CDP Cytidine-5'-diphosphate
Non-standard Residues
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MSE Selenomethionine
Glycosylation
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Code : 1EYR   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Structure of a sialic acid activating synthetase, CMP acylneuraminate synthetase in the presence and absence of CDP
Release Data : 2001-02-14
Compound :
mol_id molecule chains synonym
1 CMP-N-ACETYLNEURAMINIC ACID SYNTHETASE A,B ACYLNEURAMINATE CYTIDYLYLTRANSFERASE
ec: 2.7.7.43
Source :
mol_id organism_scientific
1 Neisseria meningitidis  (taxid:487)
Authors : Mosimann, S.C., Gilbert, M., Dombrowski, D., Wakarchuk, W., Strynadka, N.C.
Keywords : SYNTHETASE, SIALIC ACID, CDP, ACYLNEURAMINATE, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.20 Å )
Citation :

Structure of a sialic acid-activating synthetase, CMP-acylneuraminate synthetase in the presence and absence of CDP.

Mosimann, S.C.,Gilbert, M.,Dombroswki, D.  et al.
(2001)  J.Biol.Chem.  276 : 8190 - 8196

PubMed: 11113120
DOI: 10.1074/jbc.M007235200

Chain : A, B
UniProt : P0A0Z8 (NEUA_NEIME)
Reaction: EC: Evidence:
Physiological Direction:
an N-acylneuraminate + CTP = a CMP-N-acyl-beta-neuraminate + diphosphate 2.7.7.43 -
-