Brand  (β version)

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Ligands
Code Name Style Show Link
NA Sodium ion
DUT Deoxyuridine-5'-triphosphate
Non-standard Residues
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Glycosylation
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Code : 1EXC   PDBj   RCSB PDB   PDBe
Header : STRUCTURAL GENOMICS
Title : CRYSTAL STRUCTURE OF B. SUBTILIS MAF PROTEIN COMPLEXED WITH D-(UTP)
Release Data : 2000-06-14
Compound :
mol_id molecule chains
1 PROTEIN MAF A,B
Source :
mol_id organism_scientific expression_system
1 Bacillus subtilis  (taxid:1423) Escherichia coli  (taxid:562)
expression_system_vector_type: PLASMID
expression_system_plasmid: PQE30
Authors : Minasov, G., Teplova, M., Stewart, G.C., Koonin, E.V., Anderson, W.F., Egli, M., Midwest Center for Structural Genomics (MCSG)
Keywords : B.subtilis Maf protein complexed with dUTP, Structural Genomics, PSI, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG
Exp. method : X-RAY DIFFRACTION ( 2.70 Å )
Citation :

Functional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTP.

Minasov, G.,Teplova, M.,Stewart, G.C.  et al.
(2000)  Proc.Natl.Acad.Sci.USA  97 : 6328 - 6333

PubMed: 10841541
DOI: 10.1073/pnas.97.12.6328

Chain : A, B
UniProt : Q02169 (NTPPA_BACSU)
Reaction: EC: Evidence:
Physiological Direction:
dTTP + H2O = diphosphate + dTMP + H(+) 3.6.1.9 HAMAP-Rule:MF_00528, PubMed:24210219
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H2O + UTP = diphosphate + H(+) + UMP 3.6.1.9 HAMAP-Rule:MF_00528, PubMed:24210219
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CTP + H2O = CMP + diphosphate + H(+) 3.6.1.9 PubMed:24210219
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H2O + psi-UTP = diphosphate + H(+) + psi-UMP - PubMed:24210219
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5-methyl-CTP + H2O = 5-methyl-CMP + diphosphate + H(+) - PubMed:24210219
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H2O + TTP = 5-methyl-UMP + diphosphate + H(+) - PubMed:24210219
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