Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CL Chloride ion
NA Sodium ion
ZN Zinc ion
CRS M-cresol
Code : 1EV6
Header : HORMONE/GROWTH FACTOR
Title : Structure of the monoclinic form of the M-cresol/insulin R6 hexamer
Release Data : 2000-12-04
Compound :
mol_id molecule chains
1 INSULIN A,C,E,G,I,K
fragment: RESIDUES 87-107
mol_id molecule chains
2 INSULIN B,D,F,H,J,L
fragment: RESIDUES 25-54
Source :
mol_id organism_scientific
1
synthetic: yes
other_details: This sequence occurs naturally in homo sapiens (human)
mol_id organism_scientific
2
synthetic: yes
other_details: This sequence occurs naturally in homo sapiens (human)
Authors : Smith, G.D., Ciszak, E., Magrum, L.A., Pangborn, W.A., Blessing, R.H.
Keywords : R6 Hexameric Insulin, HORMONE-GROWTH FACTOR COMPLEX
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

R6 Hexameric Insulin Complexed with m-Cresol or Resorcinol

Smith, G.D.,Ciszak, E.,Magrum, L.A.  et al.
(2000)  Biochem.Biophys.Res.Commun.  56 : 1541 - 1548

PubMed: 11092919
DOI: 10.1107/S0907444900012749

Phenol Stabilizes more Helix in a New Symmetrical Zinc Insulin Hexamer

Derewenda, U.,Derewenda, Z.,Dodson, E.J.  et al.
(1989)  Nature  338 : 594 - 596

DOI: 10.1038/338594a0

Structure of a Rhombohedral R6 Insulin/Phenol Complex

Smith, G.D.,Dodson, G.G.
(1992)  Proteins  14 : 401 - 408

Chain : B, D, F, H, J, L
UniProt : P01308 (INS_HUMAN)
Reaction : -