Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CL Chloride ion
CRS M-cresol
ZN Zinc ion
Code : 1EV3
Header : HORMONE/GROWTH FACTOR
Title : Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer
Release Data : 2000-12-04
Compound :
mol_id molecule chains
1 INSULIN A,C
fragment: RESIDUES 87-107
mol_id molecule chains
2 INSULIN B,D
fragment: RESIDUES 25-54
Source :
mol_id organism_scientific
1
synthetic: yes
other_details: This sequence occurs naturally in homo sapiens (human)
mol_id organism_scientific
2
synthetic: yes
other_details: This sequence occurs naturally in homo sapiens (human)
Authors : Smith, G.D., Ciszak, E., Magrum, L.A., Pangborn, W.A., Blessing, R.H.
Keywords : R6 Hexamer, 18-A, HORMONE-GROWTH FACTOR COMPLEX
Exp. method : X-RAY DIFFRACTION ( 1.78 Å )
Citation :

R6 hexameric insulin complexed with m-cresol or resorcinol.

Smith, G.D.,Ciszak, E.,Magrum, L.A.  et al.
(2000)  Acta Crystallogr.,Sect.D  56 : 1541 - 1548

PubMed: 11092919
DOI: 10.1107/S0907444900012749

Structure of a Rhombohedral R6 Insulin/Phenol Complex

Smith, G.D.,Dodson, G.G.
(1992)  Proteins  14 : 401 - 408

Phenol Stabilizes more Helix in a new Symmetrical Zinc Insulin Hexamer

Derewenda, U.,Derewenda, Z.,Dodson, E.J.  et al.
(1989)  Nature  338 : 594 - 596

DOI: 10.1038/338594a0

Chain : B, D
UniProt : P01308 (INS_HUMAN)
Reaction : -