Brand  (β version)

PDB ID: 1ETH

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CA Calcium ion PoSSuM
C8E (hydroxyethyloxy)tri(ethyloxy)octane PoSSuM
BME Beta-mercaptoethanol PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
BMA Beta-D-mannopyranose
Modification
Code Name Show

Structure summary

Code : 1ETH   PDBj   RCSB PDB   PDBe
Header : COMPLEX (HYDROLASE/COFACTOR)
Title : TRIACYLGLYCEROL LIPASE/COLIPASE COMPLEX
Release Data : 1996-12-07
Compound :
mol_id molecule chains synonym
1 TRIACYLGLYCEROL ACYL-HYDROLASE A,C TRIACYLGLYCEROL LIPASE
ec: 3.1.1.3
mol_id molecule chains
2 COLIPASE B,D
Source :
mol_id organism_scientific organism_common
1 Sus scrofa  (taxid:9823) Pig
organ: PANCREAS
mol_id organism_scientific organism_common
2 Sus scrofa  (taxid:9823) Pig
organ: PANCREAS
Authors : Hermoso, J., Pignol, D., Kerfelec, B., Crenon, I., Chapus, C., Fontecilla-Camps, J.C.
Keywords : COMPLEX (HYDROLASE-COFACTOR), LIPID DEGRADATION, COMPLEX (HYDROLASE-COFACTOR) complex
Exp. method : X-RAY DIFFRACTION ( 2.8 Å )
Citation :

Lipase activation by nonionic detergents. The crystal structure of the porcine lipase-colipase-tetraethylene glycol monooctyl ether complex.

Hermoso, J.,Pignol, D.,Kerfelec, B.  et al.
(1996)  J.Biol.Chem.  271 : 18007 - 18016

PubMed: 8663362
DOI: 10.1074/jbc.271.30.18007

Interfacial Activation of the Lipase-Procolipase Complex by Mixed Micelles Revealed by X-Ray Crystallography

Van Tilbeurgh, H.,Egloff, M.P.,Martinez, C.  et al.
(1993)  Nature  362 : 814

Structure of the Pancreatic Lipase-Procolipase Complex

Van Tilbeurgh, H.,Sarda, L.,Verger, R.  et al.
(1992)  Nature  359 : 159

Reaction

Chain : A, C
UniProt : P00591 (LIPP_PIG)
Reaction: EC: Evidence:
Physiological Direction:
a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+) 3.1.1.3 UniProtKB:P16233
left-to-right
1,2,3-tributanoylglycerol + H2O = butanoate + dibutanoylglycerol + H(+) - UniProtKB:P16233
left-to-right
1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = (9Z)- octadecenoate + di-(9Z)-octadecenoylglycerol + H(+) - UniProtKB:P16233
left-to-right
all-trans-retinyl hexadecanoate + H2O = all-trans-retinol + H(+) + hexadecanoate - UniProtKB:P16233
left-to-right
1,2-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+) - UniProtKB:P16233
left-to-right
Chain : B, D
UniProt : P02703 (COL_PIG)
Reaction : -