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Ligands
Code Name Style Show Link
RAL Raloxifene
Non-standard Residues
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CCS Carboxymethylated cysteine
Glycosylation
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Code : 1ERR   PDBj   RCSB PDB   PDBe
Header : NUCLEAR RECEPTOR
Title : HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH RALOXIFENE
Release Data : 1998-09-16
Compound :
mol_id molecule chains synonym
1 ESTROGEN RECEPTOR A,B ESTROGEN RECEPTOR, ER-LBD, ER-ALPHA
fragment: LIGAND-BINDING DOMAIN
other_details: LIGAND-BINDING DOMAIN (DOMAIN E - RESIDUES 301-553) IN COMPLEX WITH THE SELECTIVE ANTAGONIST RALOXIFENE
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
strain: JM109
variant: C1857
gene: ER ALPHA
expression_system_strain: JM109
expression_system_variant: C1857
expression_system_plasmid: PEALPHA 35
Authors : Brzozowski, A.M., Pike, A.C.W.
Keywords : NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, STEROID, ANTAGONIST
Exp. method : X-RAY DIFFRACTION ( 2.6 Å )
Citation :

Molecular basis of agonism and antagonism in the oestrogen receptor.

Brzozowski, A.M.,Pike, A.C.,Dauter, Z.  et al.
(1997)  Nature  389 : 753 - 758

PubMed: 9338790
DOI: 10.1038/39645

Chain : A, B
UniProt : P03372 (ESR1_HUMAN)
Reaction : -