Het-PDB Navi2 (PDB: 1EP2)

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Ligands
Code	Name	Link
FAD	Flavin-adenine dinucleotide	PoSSuM
FES	Fe2/s2 (inorganic) cluster	PoSSuM
FMN	Flavin mononucleotide	PoSSuM
ORO	Orotic acid	PoSSuM

Non-standard Residues
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Download interaction data: 1EP2

Code :

1EP2 PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B COMPLEXED WITH OROTATE

Release Data :

2001-01-17

Compound :

mol_id	molecule	chains
1	DIHYDROOROTATE DEHYDROGENASE B (PYRD SUBUNIT)	A
	ec: 1.3.3.1

mol_id	molecule	chains
2	DIHYDROOROTATE DEHYDROGENASE B (PYRK SUBUNIT)	B
	ec: 1.3.3.1

Source :

mol_id	organism_scientific	expression_system
1	Lactococcus lactis (taxid:1358)	Escherichia coli (taxid:562)

mol_id	organism_scientific	expression_system
2	Lactococcus lactis (taxid:1358)	Escherichia coli (taxid:562)

Authors :

Rowland, P., Norager, S., Jensen, K.F., Larsen, S.

Keywords :

Heterotetramer, OXIDOREDUCTASE

Exp. method :

X-RAY DIFFRACTION ( 2.40 Å )

Citation :

Structure of dihydroorotate dehydrogenase B: electron transfer between two flavin groups bridged by an iron-sulphur cluster.

Rowland, P.,Norager, S.,Jensen, K.F. et al.
(2000) Structure Fold.Des. 8 : 1227 - 1238

Chain :

UniProt :

P54322 (PYRDB_LACLM)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
(S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate	1.3.1.14	PubMed:8021180, PubMed:8910599
(S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate	-	PubMed:8021180, PubMed:8910599

PDB ID: 1EP2