Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
NI Nickel (II) ion
Non-standard Residues
Code Name Show
KCX Lysine nz-carboxylic acid
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 1EJT   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : CRYSTAL STRUCTURE OF THE H219Q VARIANT OF KLEBSIELLA AEROGENES UREASE
Release Data : 2000-09-08
Compound :
mol_id molecule chains
1 UREASE ALPHA SUBUNIT C
ec: 3.5.1.5
mutation: H219Q
mol_id molecule chains
2 UREASE BETA SUBUNIT B
ec: 3.5.1.5
mol_id molecule chains
3 UREASE GAMMA SUBUNIT A
ec: 3.5.1.5
Source :
mol_id organism_scientific expression_system
1 Klebsiella aerogenes  (taxid:28451) Escherichia coli  (taxid:562)
mol_id organism_scientific expression_system
2 Klebsiella aerogenes  (taxid:28451) Escherichia coli  (taxid:562)
mol_id organism_scientific expression_system
3 Klebsiella aerogenes  (taxid:28451) Escherichia coli  (taxid:562)
Authors : Pearson, M.A., Park, I.S., Schaller, R.A., Michel, L.O., Karplus, P.A., Hausinger, R.P.
Keywords : alpha-beta barrel, nickel metalloenzyme, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.0 Å )
Citation :

Kinetic and structural characterization of urease active site variants.

Pearson, M.A.,Park, I.S.,Schaller, R.A.  et al.
(2000)  Biochemistry  39 : 8575 - 8584

PubMed: 10913264
DOI: 10.1021/bi000613o

Chain : C
UniProt : P18314 (URE1_KLEAE)
Reaction: EC: Evidence:
Physiological Direction:
2 H(+) + H2O + urea = CO2 + 2 NH4(+) 3.5.1.5 HAMAP-Rule:MF_01953, PubMed:10500143, PubMed:11015224, PubMed:1400317, PubMed:2211515, PubMed:7721685, PubMed:7855593, PubMed:7909161, PubMed:8318888, PubMed:8808930
-
Chain : B
UniProt : P18315 (URE2_KLEAE)
Reaction: EC: Evidence:
Physiological Direction:
2 H(+) + H2O + urea = CO2 + 2 NH4(+) 3.5.1.5 HAMAP-Rule:MF_01954, PubMed:10500143, PubMed:11015224, PubMed:1400317, PubMed:2211515, PubMed:7721685, PubMed:7855593, PubMed:7909161, PubMed:8318888, PubMed:8808930
-
Chain : A
UniProt : P18316 (URE3_KLEAE)
Reaction: EC: Evidence:
Physiological Direction:
2 H(+) + H2O + urea = CO2 + 2 NH4(+) 3.5.1.5 HAMAP-Rule:MF_00739, PubMed:10500143, PubMed:11015224, PubMed:1400317, PubMed:2211515, PubMed:7721685, PubMed:7855593, PubMed:7909161, PubMed:8318888, PubMed:8808930
-