Het-PDB Navi2 (PDB: 1EI2)

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Ligands
Code	Name		Style	Show	Link
NMY	Neomycin				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1EI2

Code :

1EI2 PDBj RCSB PDB PDBe

Header :

RNA

Title :

STRUCTURAL BASIS FOR RECOGNITION OF THE RNA MAJOR GROOVE IN THE TAU EXON 10 SPLICING REGULATORY ELEMENT BY AMINOGLYCOSIDE ANTIBIOTICS

Release Data :

2000-03-06

Compound :

mol_id	molecule	chains
1	TAU EXON 10 SRE RNA	A
	fragment: TAU EXON 10 SPLICING REGULATORY ELEMENT other_details: COMPLEXED WITH ANTIBIOTIC NEOMYCIN

Source :

mol_id	organism_scientific
1
	synthetic: yes other_details: This sequence occurs naturally in humans

Authors :

Varani, L., Spillantini, M.G., Goedert, M., Varani, G.

Keywords :

RNA, tau, frontotemporal dementia FTDP-17, intronic mutations, aminoglycoside, RNA major groove recognition

Exp. method :

SOLUTION NMR

Citation :

Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.

Varani, L.,Spillantini, M.G.,Goedert, M. et al.
(2000) Nucleic Acids Res. 28 : 710 - 719

PDB ID: 1EI2