Het-PDB Navi2 (PDB: 1EAO)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
BR	Bromide ion				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1EAO

Code :

1EAO PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION/DNA

Title :

THE RUNX1 Runt domain at 1.4A resolution: a structural switch and specifically bound chloride ions modulate DNA binding

Release Data :

2002-09-12

Compound :

mol_id	molecule	chains	synonym
1	RUNT-RELATED TRANSCRIPTION FACTOR 1	A,B	ACUTE MYELOID LEUKEMIA 1 PROTEIN, ONCOGENE AML-1, CORE-BINDING FACTOR, ALPHA B SUBUNIT, CBF-ALPHA B, POLYOMAVIRUS ENHANCER BINDING PROTEIN 2 ALPHA B SUBUNIT, PEBP2-ALPHA B, PEA2-ALPHA B, SL3-3 ENHANCER FACTOR 1 ALPHA B SUBUNIT, SL3/AKV CORE-BINDING FACTOR ALPHA B SUBUNIT
	fragment: RUNT DOMAIN RESIDUES 46-185 mutation: YES other_details: ENGINEERED MUTATION CYS 72 SER, CYS 81 SER

Source :

mol_id	organism_scientific	organism_common	expression_system
1	MUS MUSCULUS (taxid:10090)	MOUSE	ESCHERICHIA COLI (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_plasmid: PET11C other_details: REFOLDED FROM INCLUSION BODIES

Authors :

Backstrom, S., Wolf-Watz, M., Grundstrom, C., Hard, T.H., Grundstrom, T., Sauer, U.H.

Keywords :

TRANSCRIPTION/DNA, ACUTE MYELOID LEUKEMIA, AML, RUNX1, RUNT DOMAIN, CHLORIDE BINDING, TRANSCRIPTION FACTOR, IG FOLD, TRANSCRIPTION-DNA complex

Exp. method :

X-RAY DIFFRACTION ( 1.40 Å )

Citation :

The Runx1 Runt Domain at 1.25A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding

Backstrom, S.,Wolf-Watz, M.,Grundstrom, C. et al.
(2002) J.Mol.Biol. 322 : 259

PDB ID: 1EAO