Het-PDB Navi2 (PDB: 1E96)

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Ligands
Code	Name		Style	Show	Link
GTP	Guanosine-5'-triphosphate				PoSSuM
MG	Magnesium ion				PoSSuM

Non-standard Residues
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Download interaction data: 1E96

Code :

1E96 PDBj RCSB PDB PDBe

Header :

SIGNALING PROTEIN

Title :

Structure of the Rac/p67phox complex

Release Data :

2000-11-17

Compound :

mol_id	molecule	chains	synonym
1	RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1	A	RAC1
	mutation: YES

mol_id	molecule	chains	synonym
2	NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, RESIDUES 1-203	B	P67PHOX
	fragment: YES

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:511693)
	expression_system_strain: BL21 expression_system_plasmid: PGEX-2T

mol_id	organism_scientific	organism_common	expression_system
2	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:511693)
	expression_system_strain: BL21 expression_system_plasmid: PGEX-4T

Authors :

Lapouge, K., Smith, S.J.M., Walker, P.A., Gamblin, S.J., Smerdon, S.J., Rittinger, K.

Keywords :

SIGNALING PROTEIN, SIGNALLING COMPLEX, GTPASE, NADPH OXIDASE, PROTEIN-PROTEIN COMPLEX, TPR MOTIF

Exp. method :

X-RAY DIFFRACTION ( 2.4 Å )

Citation :

Structure of the TPR domain of p67phox in complex with Rac.GTP.

Lapouge, K.,Smith, S.J.,Walker, P.A. et al.
(2000) Mol.Cell 6 : 899 - 907

Chain :

UniProt :

P15154 (RAC1_HUMAN)

PDB ID: 1E96