Brand  (β version)

PDB ID: 1E8C

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Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
UAG Uridine-5'-diphosphate-N-acetylmuramoyl-L-alanine-D-glutamate PoSSuM
API 2,6-diaminopimelic acid PoSSuM
Non-standard Residues
Code Name Show
MSE Selenomethionine
KCX Lysine nz-carboxylic acid
Glycosylation
Code Name Emphasize
Modification
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Structure summary

Code : 1E8C   PDBj   RCSB PDB   PDBe
Header : LIGASE
Title : Structure of MurE the UDP-N-acetylmuramyl tripeptide synthetase from E. coli
Release Data : 2001-09-13
Compound :
mol_id molecule chains
1 UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE A,B
ec: 6.3.2.13
other_details: UDP-N-ACETYLMURAMYL-TRIPEPTIDE BOUND IN ACTIVE SITE
Source :
mol_id organism_scientific expression_system
1 ESCHERICHIA COLI  (taxid:562) ESCHERICHIA COLI  (taxid:562)
gene: MURE
Authors : Gordon, E.J., Chantala, L., Dideberg, O.
Keywords : LIGASE, PEPTIDOGLYCAN BIOSYNTHESIS
Exp. method : X-RAY DIFFRACTION ( 2.00 Å )
Citation :

Crystal Structure of Udp-N-Acetylmuramoyl-L-Alanyl-D-Glutamate: Meso-Diaminopimelate Ligase from Escherichia Coli

Gordon, E.J.,Flouret, B.,Chantalat, L.  et al.
(2001)  J.Biol.Chem.  276 : 10999

PubMed: 11124264
DOI: 10.1074/JBC.M009835200

Reaction

Chain : A, B
UniProt : P22188 (MURE_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D- muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N- acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6- diaminoheptanedioate 6.3.2.13 PubMed:11124264, PubMed:2269304
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