Brand  (β version)

PDB ID: 1E1T

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Ligands
Code Name Style Show Link
GOL Glycerol PoSSuM
LAD Adenosine-5'-[lysyl-phosphate] PoSSuM
MG Magnesium ion PoSSuM
POP Pyrophosphate 2- PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1E1T   PDBj   RCSB PDB   PDBe
Header : LIGASE
Title : LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH THE LYSYL_ADENYLATE INTERMEDIATE
Release Data : 2000-07-28
Compound :
mol_id molecule chains synonym
1 LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE A LYSYL-TRNA SYNTHETASE, LYSINE--TRNA LIGASE, LYSRS
ec: 6.1.1.6
Source :
mol_id organism_scientific expression_system
1 ESCHERICHIA COLI  (taxid:83333) ESCHERICHIA COLI  (taxid:562)
strain: K-12
cellular_location: CYTOPLASM
gene: LYSU
expression_system_strain: TG2
expression_system_plasmid: PXLYS5
expression_system_gene: LYSU
Authors : Desogus, G., Todone, F., Brick, P., Onesti, S.
Keywords : LIGASE, AMINOACYL-TRNA SYNTHETASE, PROTEIN BIOSYNTHESIS
Exp. method : X-RAY DIFFRACTION ( 2.4 Å )
Citation :

Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction

Desogus, G.,Todone, F.,Brick, P.  et al.
(2000)  Biochemistry  39 : 8418

PubMed: 10913247
DOI: 10.1021/BI0006722

Reaction

Chain : A
UniProt : P0A8N6 (SYK2_ECO57)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl- tRNA(Lys) 6.1.1.6 -
-