Het-PDB Navi2 (PDB: 1E1C)

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Ligands
Code	Name		Style	Show	Link
B12	Cobalamin				PoSSuM
DCA	Desulfo-coenzyme a				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1E1C

Code :

1E1C PDBj RCSB PDB PDBe

Header :

ISOMERASE

Title :

METHYLMALONYL-COA MUTASE H244A Mutant

Release Data :

2000-05-07

Compound :

mol_id	molecule	chains
1	METHYLMALONYL-COA MUTASE ALPHA CHAIN	A,C
	ec: 5.4.99.2 fragment: WHOLE MOLECULE mutation: YES other_details: CHAINS A AND C INCLUDE COENZYME B12, AND DESULPHO-COA. B12 IS PRESENT LARGELY AS REDUCED COB(II)ALAMIN, OR B12R

mol_id	molecule	chains
2	METHYLMALONYL-COA MUTASE BETA CHAIN	B,D
	ec: 5.4.99.2 fragment: WHOLE MOLECULE

Source :

mol_id	organism_scientific	expression_system
1	PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII (taxid:1752)	ESCHERICHIA COLI (taxid:562)
	strain: NCIB 9885 expression_system_strain: K38 expression_system_plasmid: PGP1-2, PMEX1 expression_system_gene: MUTA, MUTB

mol_id	organism_scientific	expression_system
2	PROPIONIBACTERIUM FREUDENREICHII SUBSP. SHERMANII (taxid:1752)	ESCHERICHIA COLI (taxid:562)
	strain: NCIB 9885 expression_system_strain: K38 expression_system_plasmid: PGP1-2, PMEX1 expression_system_gene: MUTA, MUTB other_details: THE 2 GENES MUTA (BETA CHAIN) AND MUTB (ALPHA CHAIN) ARE COEXPRESSED FROM THE SAME PLASMID

Authors :

Evans, P.R., Thoma, N.H.

Keywords :

ISOMERASE, MUTASE, INTRAMOLECULAR TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 2.62 Å )

Citation :

Protection of Radical Intermediates at the Active Site of Adenosylcobalamin-Dependent Methylmalonyl-Coa Mutase

Thoma, N.H.,Evans, P.R.,Leadlay, P.F.
(2000) Biochemistry 39 : 9213

PDB ID: 1E1C