Brand  (β version)

PDB ID: 1DXY

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Ligands
Code Name Style Show Link
SO4 Sulfate ion PoSSuM
NAD Nicotinamide-adenine-dinucleotide PoSSuM
COI 2-oxo-4-methylpentanoic acid PoSSuM
Non-standard Residues
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Structure summary

Code : 1DXY   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : STRUCTURE OF D-2-HYDROXYISOCAPROATE DEHYDROGENASE
Release Data : 1997-06-16
Compound :
mol_id molecule chains synonym
1 D-2-HYDROXYISOCAPROATE DEHYDROGENASE A D-HICDH, R-HICDH, R-2-HYDROXYISOCAPROATE DEHYDROGENASE
ec: 1.1.1.-
Source :
mol_id organism_scientific expression_system
1 Lactobacillus casei  (taxid:1582) Escherichia coli  (taxid:562)
variant: SSP. PSEUDOPLANTARUM
gene: POTENTIAL
expression_system_plasmid: PJLA601
Authors : Dengler, U., Niefind, K., Kiess, M., Schomburg, D.
Keywords : D-2-HYDROXYCARBOXYLATE DEHYDROGENASE, D-LACTATE DEHYDROGENASE, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.86 Å )
Citation :

Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution.

Dengler, U.,Niefind, K.,Kiess, M.  et al.
(1997)  J.Mol.Biol.  267 : 640 - 660

PubMed: 9126843
DOI: 10.1006/jmbi.1996.0864

Crystallization and Preliminary Characterization of Crystals of D-2-Hydroxyisocaproate Dehydrogenase from Lactobacillus Casei

Niefind, K.,Hecht, H.J.,Schomburg, D.
(1994)  J.Mol.Biol.  240 : 400

Roentgenkristallographische Untersuchungen an Drei Mikrobiellen Enzymen: D-2-Hydroxyisocaproat-Dehydrogenase Aus Lactobacillus Casei L-2-Hydroxyisocaproat-Dehydrogenase Aus Lactobacillus Confusus Alkalische Protease Aus Bacillus Alcalophilus/Variante Q59R

Niefind, K.
(1993)  Thesis 

Potential of R-2-Hydroxyisocaproate Dehydrogenase from Lactobacillus Casei for Stereospecific Reductions

Kallwass, H.K.W.
(1992)  ENZYME.MICROB.TECHNOL.  14 : 28

Cloning, Sequencing and Expression in Escherichia Coli of the D-2-Hydroxyisocaproate Dehydrogenase Gene of Lactobacillus Casei

Lerch, H.P.,Blocker, H.,Kallwass, H.  et al.
(1989)  Gene  78 : 47

Crystallization and Molecular Properties of D-2-Hydroxyisocaproate Dehydrogenase from Lactobacillus Casei

Kallwass, H.,Tsai, H.,Schuette, H.
(1987)  Fems Microbiol.Lett.  43 : 263

D-2-Hydroxyisocaproate Dehydrogenase from Lactobacillus Casei. A New Enzyme Suitable for Stereospecific Reduction of 2-Ketocarboxylic Acids

Hummel, W.,Schuette, H.,Kula, M.R.
(1985)  Appl.Microbiol.Biotechnol.  21 : 7

Reaction

Chain : A
UniProt : P17584 (DHD2_LACPA)
Reaction : -