Brand  (β version)

PDB ID: 1DQN

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Ligands
Code Name Style Show Link
IMU Phosphoric acid mono-[5-(2-amino-4-oxo-4,5-dihydro-3h-pyrrolo[3,2-D]pyrimidin-7-yl)-3,4-dihydroxy-pyrrolidin-2-ylmethyl] ester PoSSuM
IPA Isopropyl alcohol PoSSuM
MG Magnesium ion PoSSuM
POP Pyrophosphate 2- PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1DQN   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE
Release Data : 2000-07-26
Compound :
mol_id molecule chains
1 GUANINE PHOSPHORIBOSYLTRANSFERASE A,B
ec: 2.4.2.8
Source :
mol_id organism_scientific expression_system
1 Giardia intestinalis  (taxid:5741) Escherichia coli  (taxid:562)
Authors : Shi, W., Munagala, N.R., Wang, C.C., Li, C.M., Tyler, P.C., Furneaux, R.H., Grubmeyer, C., Schramm, V.L., Almo, S.C.
Keywords : protein-inhibitor complex, Mg ions, pyrophosphate, transition state analogue, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.75 Å )
Citation :

Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).

Shi, W.,Munagala, N.R.,Wang, C.C.  et al.
(2000)  Biochemistry  39 : 6781 - 6790

PubMed: 10841757
DOI: 10.1021/bi000128t

Reaction

Chain : A, B
UniProt : Q24973 (Q24973_GIAIN)
Reaction : -