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Ligands
Code Name Style Show Link
MG Magnesium ion
GDP Guanosine-5'-diphosphate
GER Geran-8-yl geran
Non-standard Residues
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CMT O-methylcysteine
Glycosylation
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Code : 1DOA   PDBj   RCSB PDB   PDBe
Header : CELL CYCLE
Title : Structure of the rho family GTP-binding protein cdc42 in complex with the multifunctional regulator rhogdi
Release Data : 2000-02-09
Compound :
mol_id molecule chains synonym
1 PROTEIN (GTP-BINDING PROTEIN) A CDC42
mol_id molecule chains synonym
2 PROTEIN (GDP-DISSOCIATION INHIBITOR 1) B RHO GDI 1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Unidentified baculovirus  (taxid:10469)
expression_system_cell: SF9 CELLS
mol_id organism_scientific organism_common expression_system
2 Bos taurus  (taxid:9913) Cattle Escherichia coli  (taxid:562)
expression_system_plasmid: PGEX-KG
Authors : Hoffman, G.R., Nassar, N., Cerione, R.C.
Keywords : GTP-binding protein, Cdc42, RhoGDI, CELL CYCLE
Exp. method : X-RAY DIFFRACTION ( 2.60 Å )
Citation :

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI.

Hoffman, G.R.,Nassar, N.,Cerione, R.A.
(2000)  Cell(Cambridge,Mass.)  100 : 345 - 356

PubMed: 10676816
DOI: 10.1016/S0092-8674(00)80670-4

Chain : A
UniProt : P60953 (CDC42_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
GTP + H2O = GDP + H(+) + phosphate 3.6.5.2 PubMed:21565175, PubMed:23940119
left-to-right
Chain : B
UniProt : P19803 (GDIR1_BOVIN)
Reaction : -